MOLECULAR DETECTION AND IDENTIFICATION OF LEISHMANIA INFECTION IN NATURALLY INFECTED SAND FLIES IN A FOCUS OF CUTANEOUS LEISHMANIASIS IN NORTHERN MOROCCO

Molecular detection and identification of Leishmania infection in naturally infected sand flies in a focus of cutaneous leishmaniasis in northern Morocco

Abstract Background Cutaneous leishmaniasis is an infectious disease caused by various species of the flagellate protozoan Leishmania.During the past 20 years, cutaneous leishmaniasis has emerged as a major public health threat in Morocco.The main objective of this study was to study the occurrence of Leishmania infection in vectors and to identify

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Evolution of Lactase Persistence: Turbo-Charging Adaptation in Growth Under the Selective Pressure of Maternal Mortality?

The emergence of the capacity to digest milk in some populations represents a landmark in human evolution, linking genetic change with a component of niche construction, namely dairying.Alleles promoting continued activity of the enzyme lactase through the life-course (lactase persistence) evolved in several global regions within the last 7,000 yea

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SOX9 governs differentiation stage-specific gene expression in growth plate chondrocytes via direct concomitant transactivation and repression.

Cartilage and endochondral bone development require SOX9 activity to regulate chondrogenesis, chondrocyte proliferation, and transition to a non-mitotic hypertrophic state.The restricted and reciprocal expression of the collagen X gene, Col10a1, in hypertrophic chondrocytes and Sox9 in immature chondrocytes epitomise the precise spatiotemporal cont

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